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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MKLN1 All Species: 22.12
Human Site: S654 Identified Species: 40.56
UniProt: Q9UL63 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UL63 NP_001138826.1 735 84768 S654 K A Q V D P L S A L K Y L Q N
Chimpanzee Pan troglodytes XP_001135240 643 74481 A563 A Q M D P L S A L K Y L Q N D
Rhesus Macaque Macaca mulatta XP_001098817 735 84767 S654 K A Q M D P L S A L K Y L Q N
Dog Lupus familis XP_850354 251 28798 I171 M D S E K H M I Y T F G G R I
Cat Felis silvestris
Mouse Mus musculus O89050 735 84859 S654 K A Q M D P L S A L K Y L Q N
Rat Rattus norvegicus Q99PV3 735 84815 S654 K A Q M D P L S A L K Y L Q N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511026 709 82133 S628 K A Q T D P L S A L K Y L Q N
Chicken Gallus gallus NP_001025944 733 84525 S652 K A Q T D P L S A L K Y L Q N
Frog Xenopus laevis NP_001087072 727 84623 C646 C A Q K E P L C A L K Y L Q N
Zebra Danio Brachydanio rerio NP_997859 729 84358 N648 K A Q T E P L N A L K Y L Q N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610801 853 97490 K706 M T R Q D P L K A M Q Y L R H
Honey Bee Apis mellifera XP_624921 760 87304 Q679 I D H N D A E Q T K E F Q L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793226 1390 161226 M671 T A M G N P M M A L S Y L Q R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.3 99.7 33.8 N.A. 99.1 99.3 N.A. 94.1 96.1 89.9 89.1 N.A. 42.3 54 N.A. 32.6
Protein Similarity: 100 87.4 100 34.1 N.A. 99.5 99.8 N.A. 95.7 98.3 95 95.2 N.A. 61.3 70.9 N.A. 41.9
P-Site Identity: 100 0 93.3 0 N.A. 93.3 93.3 N.A. 93.3 93.3 73.3 80 N.A. 40 6.6 N.A. 46.6
P-Site Similarity: 100 13.3 100 13.3 N.A. 100 100 N.A. 93.3 93.3 80 93.3 N.A. 73.3 20 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 70 0 0 0 8 0 8 77 0 0 0 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 16 0 8 62 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 8 16 0 8 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 0 0 0 8 8 0 0 % G
% His: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % I
% Lys: 54 0 0 8 8 0 0 8 0 16 62 0 0 0 0 % K
% Leu: 0 0 0 0 0 8 70 0 8 70 0 8 77 8 8 % L
% Met: 16 0 16 24 0 0 16 8 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 8 8 0 0 8 0 0 0 0 0 8 62 % N
% Pro: 0 0 0 0 8 77 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 62 8 0 0 0 8 0 0 8 0 16 70 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 0 16 8 % R
% Ser: 0 0 8 0 0 0 8 47 0 0 8 0 0 0 0 % S
% Thr: 8 8 0 24 0 0 0 0 8 8 0 0 0 0 0 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 8 77 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _